Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma and chronic obstructive pulmonary disease (COPD). They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Bronchodilators are drugs that open up (dilate) the breathing passages by relaxing the bronchial smooth muscle. Pharmacology is a medical science that forms a backbone of the medical profession as drugs form the corner stone of therapy in human diseases. They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around the use of these drugs remain. Actions: open the bronchi and allow more air to enter the lungs, which in turn completely or partially relieves respiratory distress. Bronchodilators (Contd) Xanthine Derivatives Main xanthine used clinically is theophylline Theophylline is a bronchodilator which relaxes smooth muscle of the bronchi, it is used for reversible airway obstruction One proposed mechanism of action is that it acts by inhibiting phosphodiesterase, thereby increasing cAMP, leading to bronchodialtion. Sympathomimetic Bronchodilators: Actions and Uses. In asthma and COPD, bronchoconstriction and mucus secretion are increased and the airways become hyperresponsive to contractile agents. Original PPT modified by: Anita A. Kovalsky, R.N., M.N.Ed.. World's Best PowerPoint Templates - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. They make breathing easier for people with asthma or other lung conditions.. Bronchodilators include short acting beta2-agonists such as albuterol, long-acting beta2-agonists (such as salmeterol, formoterol), anticholinergic agents (eg, ipratropium) and theophylline. … There is therefore considerable interest in understanding how to optimize the use of our existing classes of bronchodilator and in identifying novel classes of bronchodilator drugs. Bronchodilators are the mainstay therapy in COPD, as they increase expiratory flow by decreasing airway smooth muscle tone, thus leading to enhanced lung emptying. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Therefore, it is of utmost importance to describe the pharmacological basis of therapeutics in order to maximize the benefits and The cholinergic blocking drug ipratropium bromide (Atrovent) is used for bronchospasm associated with COPD, chronic bronchitis, and emphysema in emergent situations. Start studying PHARMACOLOGY: ANTICHOLINERGIC BRONCHODILATORS. 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